So I ordered and then picked up 3 Puxing 888K's from North Trail Sports yesterday.
I know there have been a lot of threads in the past about issues programming them, and I went through quite my own issues as well.
Regardless of the Prolific driver I had tried to use, I kept having issues properly connecting to the radios.
So I did a system restore and tried the 3.2.0.0 drivers found here ...
http://miklor.com/COM/UV_Drivers.php
And I used the older Puxing 888 UV software (although now that the drivers work the latest software may also work).
http://blog.murs-radio.com/?page_id=416
And I finally got it with my Window's 7 laptop.
I hope it helps.
Dimitri